Ho phaella ho liphetoho tsa mokhoa oa bophelo le ho khomarela mekhoa e metle, tlatsetso e sa tloaelehang ea lintho tsa tlhaho tse khahlanong le botsofali hape ke mokhoa o bonolo le o bonolo oa ho thibela botsofali. Ho latela tataiso ea lipatlisiso (NAD + metabolic regulation) le liphetho tsa hajoale tsa anti-botsofali le lits'ebetso tse amehang haholo.hape le"moholi bokong"ka mor'a COVID-19,rona'Ke rata ho hlahisa tse 'maloa tse ntlemetsoako e thibelang botsofaliho tsoa ho li-supplement tse rekisoang tse chesang ho Amazon.
1. NAD+ supplements (NMN, NR, NADH)
Maemo a NAD + a theoha ka botsofali, e leng se lebisang ho mpefaleng ho amehang maemo a NAD +. Lelapa la acetylase (li-sirtuins, tse atisang ho phatlalatsoa e le liprotheine tsa nako e telele) ha li khone ho boloka ts'ebetso e tloaelehileng, e le hore mesebetsi e mengata e molemo ho bophelo bo botle ba li-sirtuin e ke ke ea etsoa, e leng e 'ngoe ea mabaka a bohlokoa a ho tsofala.Iho nka NMN (nicotinamide mononucleotide), NR (nicotinamide riboside) kapa NADH (nicotinamide adenine dinucleotide) e ka thusa lisele ho eketsa maemo a NAD+, 'me tsena ka tlhaho li teng liseleng le lijong tsa tlhaho..Hajoale, ho na le lithuto tsa bongaka tse makholo ho NMN, NR, le NADH, tse shebaneng le likarolo tse fapaneng tse kang anti-botsofali, lefu la tsoekere, metabolism, le temoho.
2. Pyrroloquinoline quinone (PQQ)
PQQ ke redox coenzyme le antioxidant e matla. E boetse e teng lijong tse fapaneng. Likahare tsa PQQ 'meleng oa motho li tlase haholo. PQQ liseleng tsa motho e ka tsoa lijong kapa likokoana-hloko. Lijo tse nang le PQQ e ngata li kenyelletsa: natto, parsley, tee e tala, tholoana ea kiwi, papaya, tofu, joalo-joalo PQQ e ka susumetsa biosynthesis ea mitochondrial hape ke activator ea li-sirtuin. Melemo e ka bang teng ea bophelo bo botle ea PQQ e kenyelletsa: ho ntlafatsa boroko, anti-diabetes, anti-arthritis, anti-osteoporosis, ho fokotsa kotsi ea pelo ea ischemia-reperfusion, ho thibela tyrosinase, ho ntlafatsa tsoalo.
3. Fisetin
Fisetin, e tsejoang hape e leMosi oa Sefate sa Mosi , ke flavonol e entsoeng ke semela le pigment e tloaelehileng ea semela e fumanoang merohong e mengata e tloaelehileng le litholoana tse kang fragole, liapole, li-persimmons, eiee le likomkomere. E eketsa nako ea bophelo ba litoeba tse tsofetseng ka 10%, e fokotsa matšoao a botsofali liseleng, 'me e liehisa mafu a amanang le botsofali. Mokhoa o thibelang botsofali oa fisetin ke hore o ka tlosa lisele tsa senescent mme o sebetsa e le synolytic. Ho bokellana ha lisele tsa senescent le hona ke sesosa sa bohlokoa sa botsofali le mafu a amanang le botsofali. Liphuputso li fumane hore melemo ea bophelo bo botle ea fisetin e kenyelletsa: anti-oxidation, anti-inflammation, tšireletso ea pelo, ts'ireletso ea kelello, thibelo ea botenya le mathata a metabolism.
4. Urolithin A
Urolithin A e fumaneha liseleng tse fapaneng tsa 'mele oa motho. Empa urolithin A ha se molek'hule ea tlhaho lijong 'me e hlahisoa ke libaktheria tse ling tsa mala tse metabolize ellagic acid le ellagitannins. Li-precursors tsa urolithin A - ellagic acid le ellagitannins - li fumaneha haholo lijong tse fapaneng, joalo ka likharenate, fragole, raspberries le walnuts. Hore na 'mele oa motho o ka hlahisa urolithin A e lekaneng ka mor'a ho ja li-precursers tsena hape o fokotsoa ke mefuta-futa ea likokoana-hloko tsa mala. Botsofali bo lebisa ho fokotseha ha bokhoni ba lisele tsa autophagic, bo lebisang ho bokelleng ha mitochondria e senyehileng, ho hlahisa khatello ea oxidative, le ho khothaletsa ho ruruha. Urolithin A e ntlafatsa bophelo bo botle ba mitochondrial ka ho eketsa autophagy.
5. Spermidine
Spermidine ke polyamine ea tlhaho eo mahloriso a eona a intracellular a fokotsehang nakong ea botsofali ho batho, 'me ho ka' na ha e-ba le kamano pakeng tsa ho fokotseha ha spermidine le ho senyeha ho amanang le lilemo. .Liphello tse ka 'nang tsa e-ba teng tsa spermidine li kenyelletsa: ho fokotsa khatello ea mali, ho matlafatsa tšireletso ea antioxidant, ho eketsa bioavailability ea arginine, ho fokotsa ho ruruha, ho fokotsa ho satalla ha methapo, ho laola khōlo ea lisele.
Nako ea poso: Mar-02-2023
