Coenzyme Q10 ke eona feela ntho ea coenzyme Q 'meleng oa motho, e tsejoang hape e le ubiquinone. Coenzyme Q10 e ipakile e na le antioxidant, free radical scavenging, anti-tumor le ho ntlafatsa litlamorao tsa ts'ireletso ea motho, ka hona e imolla mokhathala le ho ntlafatsa boikoetliso, le anti-botsofali. Le litlamorao tse fapaneng tsa bophelo bo botle joalo ka ts'ireletso ea pelo.
ngoe,Mesebetsi ea fisioloji ea coenzyme Q10
1. Free radical scavenging and antioxidant function (ho lieha ho tsofala lebotle)
Coenzyme Q10 e teng libakeng tse peli: e fokotsehile ebile e na le oxidized. Har'a tsona, coenzyme Q10 e fokotsehileng e na le oxidized habonolo mme e ka thibela peroxidation ea lipids le liprotheine le ho senya li-radicals tsa mahala. Fokotsa khatello ea oxidative, e leng phello e mpe e hlahisoang ke li-radicals tsa mahala 'meleng' me ke ntho ea bohlokoa e lebisang botsofaling le maloetse. Coenzyme Q10 ke antioxidant e sebetsang hantle ebile e na le free radical scavenger e ka fokotsang tšenyo e bakiloeng ke khatello ea oxidative.Coenzyme Q10 e ka ntlafatsa bioavailability ea letlalo, ea lokisa letlalo, ea eketsa bongata ba keratinocyte, ea ntlafatsa matla a antioxidant ea lisele tsa letlalo, ea thibela botsofali ba letlalo, 'me ea fihlela phello ea kalafo ho dermatitis, makhopho, li-bedsores, liso tsa letlalo le mafu a mang a letlalo. Coenzyme Q10 e ka boela ea khothalletsa ho thehoa ha lisele tsa epithelial le benignization ea lisele tsa granulation, ho thibela ho thehoa ha lebali, le ho khothalletsa ho lokisoa ha lebali; thibela mosebetsi oa phosphotyrosinase, thibela ho thehoa ha melanin le matheba a lefifi; fokotsa botebo ba wrinkles, ntlafatsa botsoa ba letlalo; 'me e ka eketsa pepeneneng Ho bokellana ha li-amino acid ho eketsa mongobo oa letlalo; e na le phello e ntle ho ntlafatseng letlalo le lerootho, ho fokotsa masoba, le ho khutlisetsa letlalo la pele boreleli, elasticity le thepa ea mongobo.
2. Ntlafatsa ts'ireletso ea motho le anti-tumor
Khale koana ka 1970, liphuputso tse amehang li ile tsa tlaleha hore ho nka coenzyme Q10 ho litoeba ho ka eketsa tšebetso ea lisele tsa 'mele tsa ho itšireletsa mafung ho bolaea libaktheria, ho ntlafatsa likarabo tsa antibody, le ho susumetsa keketseho ea palo ea li-immunoglobulins le li-antibodies. Nikbakht et al. e ithutile hore ha baatlelete ba banna ba nka Coenzyme Q10 ka mor'a litlhōlisano tse latellanang, palo ea li-neutrophils ka plasma ea tsona e fokotsehile haholo. Ka hona, ba lumela hore Coenzyme Q10 e molemo ho sireletsa sesole sa baatlelete le ho matlafatsa tšireletso ea 'mele. Bakeng sa batho ba tloaelehileng, ho nka Coenzyme Q10 ka molomo ka mor'a ho sebetsa ho feta tekano ho ka ntlafatsa mokhathala oa 'mele le ho matlafatsa matla a' mele.
Lipatlisiso tse entsoeng lilemong tsa morao tjena li bontšitse hore coenzyme Q10, e le ntho e matlafatsang 'mele ea ho itšireletsa mafung, e ka bapala karolo e ntle ho ntlafatsa tšireletso ea' mele le anti-tumor, 'me e na le phello e itseng ea kliniki mofetšeng o tsoetseng pele oa metastatic.
3. Matlafatsa matla a pelo le ho matlafatsa matla a boko
Coenzyme Q10 ke e 'ngoe ea lintho tsa bohlokoahali' meleng oa motho. Likahare tsa eona li phahame haholo myocardium. Ha e haella, e tla baka ts'ebetso e sa lekaneng ea pelo, e lebisa ho phallo e mpe ea mali, ho fokotsa matla a ho sebetsa ha pelo, 'me qetellong ho baka lefu la pelo. Liphello tse ka sehloohong tsa coenzyme Q10 ho myocardium ke ho khothalletsa phosphorylation ea cellular, ho ntlafatsa metabolism ea matla a myocardial, ho fokotsa tšenyo ea ischemia ho myocardium, ho eketsa phallo ea mali ea pelo, ho ntlafatsa tšubuhlellano e sa foleng le ho hanyetsa arrhythmias, kahoo ho sireletsa myocardium. Ntlafatsa mosebetsi oa pelo le ho fana ka matla a lekaneng bakeng sa myocardium. Liphuputso tsa bongaka li bontša hore ho feta 75% ea bakuli ba lefu la pelo ba ntlafalitse boemo ba bona haholo ka mor'a ho nka Coenzyme Q10. Coenzyme Q10 ke activator ea metabolism e ka kenyang phefumoloho ea lisele, e fana ka oksijene le matla a lekaneng ho cardiomyocyte le lisele tsa boko, ho boloka lisele li le boemong bo botle le bo botle, kahoo li thibela liketsahalo tsa pelo le methapo ea pelo.
4. Laola lipids tsa mali
Ha li-statins li theola lipids tsa mali, li boetse li thibela motsoako o ikemetseng oa 'mele oa coenzyme Q10. Ka hona, batho ba nang le lipids tse phahameng tsa mali ba tlameha ho nka coenzyme Q10 ha ba nka li-statins ho fihlela phello e ntle ea ho theola lipid. Coenzyme Q10 e ka fokotsa litaba tsa "low-density lipoprotein" e kotsi 'meleng oa motho, ea thibela lipoprotein tsa "low-density lipoprotein" ho kenella ka har'a lekhalo la lisele tsa endothelial, ea fokotsa sebopeho sa lipids leboteng le kahare la methapo, le ho thibela lipids ho theha atherosclerotic. plaques leboteng la methapo ea mali. , ha e ntse e eketsa ts'ebetso ea lipoprotein tse phahameng, ho tlosa lithōle ka potlako, chefo le li-plaque tse entsoeng leboteng le ka hare la methapo ea mali, ho laola lipids tsa mali le ho thibela ho thehoa ha atherosclerosis.
tse pedi, Tšireletseho ea Coenzyme Q10
'Mele oa motho ha o na maemo a phahameng a Coenzyme Q10 ha a tsoaloa, empa litaba li fihla tlhōrōng ea eona ho pota lilemo tse 20. Ka mor'a lilemo tse 25, bokhoni ba ho kopanya Coenzyme Q10 butle-butle bo fokotseha. Ha lilemo li ntse li eketseha, Coenzyme Q10 likarolong tse fapaneng tsa 'mele le lisele tse' mele e fokotseha butle-butle, 'me Coenzyme Q10 ka pelong e fokotseha haholo. Ha litaba tsa Coenzyme Q10 'meleng oa motho li fokotseha ka 25% Nakong e tlang, mafu a fapaneng a tla hlaha, kahoo tlatsetso e sa tloaelehang ea Coenzyme Q10 e hlokahala haholo. Ntho e tsotehang ea Coenzyme Q10 ke hore ha e na chefo, ha e na teratogenic ebile ha e na litla-morao tse totobetseng, 'me e sireletsehile haholo bakeng sa tšebeliso ea meriana. Coenzyme Q10, joalo ka e 'ngoe ea li-coenzymes tsa bohlokoahali' meleng oa motho, e sebelisoa haholo tlhokomelong ea bongaka.
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