Mokhoa o mosoeu oa arbutin
Likahare le kabo eamelanin ke lintlha tse ka sehloohong tse khethollang botebo ba 'mala oa letlalo. Melanin e hlahisoa ka melanocyte karolong ea basal ea epidermis ea letlalo. Qetellong e thehoa ho tloha tyrosine tlas'a ketso ea tyrosinase ka letoto la liphetoho tse rarahaneng tsa biochemical. E fetisoa ho tloha karolong ea basal ho ea karolong e ka ntle ea epidermis ho tloha ka hare ho ea ka li-synapses. mebala letlalo.
Tyrosinase e na le ts'ebetso ea tyrosine hydroxylase (e susumetsang tyrosine ho hlahisa dopa) le ts'ebetso ea dopa oxidase (ho etsa hore dopa e hlahise dopaquinone). Ts'ebetsong ea tlhahiso ea melanin, e sebetsa e le enzyme e ka sehloohong e fokotsang sekhahla. Mosebetsi oa eona o lekanya boholo ba melanin e entsoeng.
Arbutin ke tyrosinase inhibitor e ka thibelang ts'ebetso ea tyrosinase ka katleho ntle le ho ama mahloriso a ho ata ha lisele. E hlōlisana bakeng sa ho tlama dopa ka ho tlama ha eona ka ho toba ho tyrosinase. sebaka, e thibela tlhahiso ea dopa le dopaquinone, kahoo e kena-kenana le melanocyte le ho thibela tlhahiso ea melanin. Ka nako e ts'oanang, e boetse e na le mosebetsi oa ho hlapolla melanin e entsoeng, ho potlakisa ho bola le ho tsoa ha melanin, ho fokotsa mebala ea letlalo, le ho tlosa matheba le matheba.
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Nako ea poso: Feb-23-2024
